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Nov 28, 2008
CHIHUAHUA, MEXICO - (PR NEWSWIRE) -- NOVEMBER 28, 2008 -- Mexoro Minerals Ltd. Continues Exploratory Drilling At Its Cieneguita Project. (MXOM.OB) (Frankfurt: OYA1).

Mexoro Minerals is pleased to announce that it continues exploratory and infill drilling at its Cieneguita project located in Chihuahua, Mexico. To date, a total of 91 holes have been drilled with an additional 5,000 meters of drilling still to be completed. Of the 91 holes drilled, Mexoro is still waiting for the assay results of 37 of those holes from ALS Chemex. As well, Delve Consulting is preparing a NI 43-101 compliant report updating the information released in August 2008. This report will contain the results from 54 holes and will be updated again when the drill program has been completed. The report from Delve Consulting is expected to be finished in early December 2008.

Barry Quiroz, President says, "The alteration and mineralization assemblages observed in the drill cores from the additional 42 holes completed to date seems to confirm the lateral continuity and depth extent of the main mineralization of the system. We are anxiously waiting for the assay results to ensure that our in-house mineralization model is working to delineate a gold-silver deposit with significant lead and zinc component. We are pleased with the size of the initial resource estimate, especially since it does not include most of the holes from the infill drilling program collared in and around the higher grade areas.

Reconnaissance-style exploration and a detailed mapping and sampling program of the Piedras Blancas area, 500 meters to the south of the Cieneguita project, are currently in progress, aimed to identify additional drilling targets within Mexoro's concessions. Recent geological mapping continues to show intense and extensive alteration and quartz veins stockworked areas, where gold anomalies varying from 0.28 and 4.01 g/t Au. Drilling targets and drilling program are expected to be ready during second quarter 2009.

These results have been prepared under the supervision of Barry Quiroz, MSc., Mexoro VP of Exploration. He has the expertise and authority to verify the authenticity and validity of this data. The qualified person who has reviewed this news release is Dana C. Durgin, MSc. Economic Geology. He is a Certified Professional Geologist (CPG #10364) with the American Institute of Professional Geologists, and a Registered Professional Geologist in Wyoming (PG-2886).

About Mexoro:

Mexoro Minerals Ltd. is an exploration company focused on exploring for precious metals in the traditionally mineral rich Sierra Madre region of Chihuahua, Mexico and controls three historical gold-silver mines for which additional exploration has confirmed significant mineral potential. The Company also has claims on additional properties in the state of Chihuahua.

This Press Release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The Company has tried, whenever possible, to identify these forward-looking statements using words such as "anticipates," "believes," "estimates," "expects," "plans," "intends," "potential" and similar expressions. These statements reflect the Company's current beliefs and are based upon information currently available to it. Accordingly, such forward-looking statements involve known and unknown risks, uncertainties and other factors which could cause the Company's actual results, performance or achievements to differ materially from those expressed in or implied by such statements. The Company undertakes no obligation to update or advise in the event of any change, addition or alteration to the information catered in this Press Release including such forward-looking statements.

Cautionary Note to US Investors:

All mineralized material have been calculated in accordance with the definition standards on mineral resources and mineral reserves of the Canadian Institute of Mining, Metallurgy and Petroleum and disclosed as required by the Canadian Securities Administrators pursuant to Canadian National Instrument 43-101, commonly referred to as NI 43-101. U.S. SEC reporting requirements for disclosure are governed by SEC Industry Guide 7. NI 43-101 and Industry Guide 7 differ materially.

The United States Securities and Exchange Commission allows disclosure for U.S. reporting purposes only on mineral deposits that a company can economically and legally extract or produce. We use certain terms in this press release, such as "reserves," "resources," "proven," "probable," "measured," "indicated," or "inferred" which may not be consistent with the reserve definitions established by Industry Guide 7. We caution U.S. investors that while these terms are recognized and required by Canadian Securities Administrators pursuant to National Instrument 43 101, the U.S. Securities and Exchange Commission does not recognize it. In this press release the term "inferred resources" have a great amount of uncertainty as to their existence, and great uncertainty as to their economic and legal feasibility. It cannot be assumed that all or any part of an Inferred Mineral Resource will ever be upgraded to a higher category. Under Canadian Securities Administration rules, estimates of Inferred Mineral Resources may not form the basis of feasibility or pre feasibility studies. U.S. investors are cautioned not to assume that part or all of an inferred resource exists, or is economically or legally minable. U.S. investors are urged to consider closely the disclosure in our filings with the SEC. You can review and obtain copies from the SEC website at http://www.sec.gov/edgar.shtml.

Corporate Headquarters
Mexoro Minerals Ltd.
C. General Retana #706
Col. San Felipe,
Chihuahua, Chih. C.P. 31203
Mexico

Tel: +52 (614) 426-5505